食品添加劑網(wǎng)訊  2023年2月24日，據歐盟食品安全局（EFSA）消息，應歐盟委員會(huì )要求，歐盟動(dòng)物飼料添加劑和產(chǎn)品（FEEDAP）研究小組就一種β-甘露聚糖酶（endo-1,4-β-d-mannanase）作為育肥雞、育肥火雞、飼養用于產(chǎn)蛋的雞、飼養用于繁殖的火雞、飼養用于產(chǎn)蛋的小型家禽物種、育肥豬、斷奶仔豬和小型豬種飼料添加劑的安全性和有效性發(fā)表科學(xué)意見(jiàn)。

　　據了解，這種β-甘露聚糖酶由Paenibacillus lentus DSM 33618產(chǎn)生。經(jīng)過(guò)評估，專(zhuān)家小組認為在建議的使用條件下該添加劑對目標物種、消費者和環(huán)境是安全的。該添加劑在32，000 U/kg飼料水平下對育肥雞、飼養用于產(chǎn)蛋的雞、飼養用于產(chǎn)蛋的小型家禽物種、育肥豬和小型豬種是有效的，在48，000 U/kg飼料水平下對育肥火雞、飼養用于繁殖的火雞和斷奶仔豬有效。部分原文報道如下：

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of endo-1,4-β-d-mannanase (Hemicell® HT/HT-L) produced by a genetically-modified strain of Paenibacillus lentus (DSM 33618) as a zootechnical feed additive for chickens and turkeys for fattening, chickens reared for laying, turkeys reared for breeding, minor poultry species to point of lay, pigs for fattening, piglets (weaned) and minor porcine species. The production strain was obtained from a Paenibacillus lentus recipient strain that has been evaluated previously by EFSA and considered to be safe. The genetic modification does not raise safety concerns and there were no antibiotic resistance genes from the genetic modification in the production strain. Viable cells and the DNA of the production strain were not found in the intermediate product used to formulate the additive. Hemicell® HT/HT-L produced by Paenibacillus lentus DSM 33618 is considered safe for the above-mentioned target species at the intended conditions of use. The use of Hemicell® HT/HT-L as a feed additive raises no concerns for the consumer or for the environment. Hemicell® HT/HT-L is not irritant to the skin and eyes but is regarded as a dermal sensitiser and a potential respiratory sensitiser. The additive has a potential to be efficacious at 32,000 U/kg in chickens for fattening, chickens reared for laying, minor poultry species for fattening or reared for laying/breeding, pigs for fattening and minor porcine species, and at 48,000 U/kg in turkeys for fattening, turkeys reared for breeding and weaned piglets.

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